{"id":5939,"date":"2020-05-24T21:08:37","date_gmt":"2020-05-24T19:08:37","guid":{"rendered":"https:\/\/blog.uchceu.es\/odontologia\/?p=5939"},"modified":"2020-05-24T21:15:22","modified_gmt":"2020-05-24T19:15:22","slug":"streptococcus-pyogenes-resistente-a-la-eritromicina","status":"publish","type":"post","link":"https:\/\/blog.uchceu.es\/odontologia\/streptococcus-pyogenes-resistente-a-la-eritromicina\/","title":{"rendered":"!Streptococcus pyogenes resistente a la eritromicina\u00a1"},"content":{"rendered":"

La eritromicina<\/strong><\/span> es un antibi\u00f3tico de la familia de los macr\u00f3lidos. Act\u00faa inhibiendo la s\u00edntesis de prote\u00ednas bacterianas al unirse a la subunidad 50S del ribosoma y previniendo la translocaci\u00f3n de p\u00e9ptidos. Las concentraciones cr\u00edticas separan las cepas sensibles de las cepas intermedias y estas \u00faltimas de las cepas resistentes: S (sensible)<= 1 mg\/l y R (resistente) > 4 mg\/l.<\/p>\n

En 1949, Abelardo Aguilar<\/strong> (Imagen 1)<\/em>, un cient\u00edfico filipino, envi\u00f3 varias muestras de suelo a su Eli Lilly. El equipo de investigaci\u00f3n de la empresa, dirigido por J. M. McGuire, aisl\u00f3 con \u00e9xito la eritromicina y se comercializ\u00f3 ya en 1952 bajo la marca Ilosone.<\/p>\n

\u00ab\u00bfQui\u00e9n describe e identifica el Streptococcus pyogenes<\/em>?\u00bb<\/h3>\n

La primera descripci\u00f3n reconocida del estreptococo fue realizada por\u00a0 Theodor Billroth<\/strong> (Imagen 1) <\/em>en 1874. Describi\u00f3 \u00abpeque\u00f1os organismos aislados u organizados en parejas, a veces en cadenas de 4 a 20 o m\u00e1s\u00bb. Sin embargo, la primera caracterizaci\u00f3n de estos estreptococos Gram positivos\u00a0fue dada por Louis Pasteur<\/strong> (Imagen 1) <\/em>en 1879. Este bacteriol\u00f3go franc\u00e9s a\u00edslo esta bacteria del \u00fatero y muestras de sangre en mujeres que sufr\u00edan fiebre puerperal (relacionada con el parto).<\/p>\n

\"\"
Imagen 1. Abelardo Aguilar, Theodor Billroth, Louis Pasteur.<\/figcaption><\/figure>\n

En 1993, Rebecca Craighill Lancefield<\/strong> estudi\u00f3 la estructura antig\u00e9nica de los estreptococos y los consigui\u00f3 clasificar seg\u00fan estos ant\u00edgenos situados por encima del peptidoglucano, creando la conocida Clasificaci\u00f3n de Lancefield.<\/strong><\/span>\u00a0<\/strong>En esta clasificaci\u00f3n, el Streptococcus pyogenes<\/em> se sit\u00faa en el grupo A.<\/p>\n

\u00abStreptococcus pyogenes<\/em>-estreptococo del grupo A\u00bb<\/em><\/h3>\n

Patogenia:<\/h2>\n

La patogenicidad del estreptococo \u00df-hemol\u00edtico del grupo A es particularmente amplia, y abarca desde infecciones benignas, como la angina, faringitis<\/em><\/strong> o el imp\u00e9tigo, hasta afecciones posestreptoc\u00f3cicas potencialmente debilitantes. Adem\u00e1s, infecciones invasivas graves, como la fascitis necrotizante o el temido s\u00edndrome de shock t\u00f3xico estreptoc\u00f3cico.<\/p>\n

\"\"<\/p>\n

<\/h2>\n

Tratamiento:<\/h2>\n

Los antibi\u00f3ticos \u00df-lact\u00e1micos, son actualmente el tratamiento est\u00e1ndar para las infecciones estreptoc\u00f3cicas.\"\" Desde hace varios a\u00f1os, la resistencia a determinadas familias de antibi\u00f3ticos est\u00e1 aumentando, en particular los macr\u00f3lidos, lincosamidas, estreptograminas (muy prescritas en pediatr\u00eda, o en adultos o en alergias a \u00df-lact\u00e1micos ). Este hecho desencadena una resistencia a estos antibi\u00f3ticos produciendo un gran problema salud.<\/p>\n

Finalmente, dado el probable resurgimiento de infecciones invasivas graves y el tratamiento r\u00e1pido de las infecciones benignas debidas a esta bacteria es de particular importancia utilizar correctamente los antibi\u00f3ticos.<\/h6>\n
\n

 <\/p>\n

El contenido de este post es el resultado del trabajo de seis alumnos de segundo curso del grado de Odontolog\u00eda: ELEONORE CHALMIN, VICTOIRE LECLERCQ, ALIZEE DE SIESTER, ANTONIN AUBERT, MEDI VEMINARDI, JEAN LABORDE<\/strong><\/em> .\u00a0Dicho\u00a0 trabajo forma parte del Proyecto de Innovaci\u00f3n y Mejora de la Docencia titulado \u201cEscribir para aprender: el blog como recurso did\u00e1ctico\u201d.<\/strong><\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

La eritromicina es un antibi\u00f3tico de la familia de los macr\u00f3lidos. Act\u00faa inhibiendo la s\u00edntesis de prote\u00ednas bacterianas al unirse a la subunidad 50S del ribosoma y previniendo la translocaci\u00f3n de p\u00e9ptidos. Las concentraciones cr\u00edticas separan las cepas sensibles de las cepas intermedias y estas \u00faltimas de las cepas resistentes: S (sensible)<= 1 mg\/l y […]<\/p>\n","protected":false},"author":395,"featured_media":5966,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[662,664,663],"class_list":{"0":"post-5939","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nuestros-alumnos","8":"tag-eritromicina","9":"tag-faringitis","10":"tag-s-pyogenes"},"yoast_head":"\n!Streptococcus pyogenes resistente a la eritromicina\u00a1<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.uchceu.es\/odontologia\/streptococcus-pyogenes-resistente-a-la-eritromicina\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"!Streptococcus pyogenes resistente a la eritromicina\u00a1\" \/>\n<meta property=\"og:description\" content=\"La eritromicina es un antibi\u00f3tico de la familia de los macr\u00f3lidos. 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