{"id":2427,"date":"2015-11-23T17:38:33","date_gmt":"2015-11-23T16:38:33","guid":{"rendered":"https:\/\/blog.uchceu.es\/farmacia\/?p=2427"},"modified":"2022-11-21T10:51:46","modified_gmt":"2022-11-21T09:51:46","slug":"efectos-positivos-de-la-espironolactona-frente-a-la-hipertension-resistente","status":"publish","type":"post","link":"https:\/\/blog.uchceu.es\/farmacia\/efectos-positivos-de-la-espironolactona-frente-a-la-hipertension-resistente\/","title":{"rendered":"Efectos positivos de la espironolactona frente a la hipertension resistente"},"content":{"rendered":"
\n
\"Diapositiva1\"<\/a><\/figure>\n<\/div>\n\n\n

Cuando hablamos de  hipertensi\u00f3n resistente<\/strong>, nos referimos a la presi\u00f3n arterial NO controlada<\/span> tratada con los medicamentos est\u00e1ndar. Este tratamiento se basa en tres grupos farmacol\u00f3gicos recomendados para disminuir la presi\u00f3n arterial en la m\u00e1xima dosis tolerada:<\/p>\n\n\n\n

  • Inhibidor de la enzima convertidora de angiotensina (IECA) o antagonista de los receptores de angiotensina II (ARAII).<\/li>
  • Calcioantagonista<\/li>
  • Diur\u00e9tico tiaz\u00eddico.<\/li><\/ul>\n\n\n\n

    Hasta ahora, no hay ning\u00fan f\u00e1rmaco antihipertensivo definido para incluir en el tratamiento de los pacientes con hipertensi\u00f3n resistente.<\/p>\n\n\n\n

    Por ello, se inici\u00f3 el estudio PATHWAY-2 con el objetivo de confirmar que si la hipertensi\u00f3n resistente es causada fundamentalmente por la retenci\u00f3n excesiva de sodio, la espironolactona (antagonista de la aldosterona, excretor de sodio y agua) tendr\u00eda una eficacia superior frente a otros f\u00e1rmacos para disminuir la presi\u00f3n arterial resistente en el tratamiento combinado.<\/p>\n\n\n\n

    Es un estudio cruzado y a doble ciego controlado con placebo, en el cual 230 pacientes completaron todos los ciclos del tratamiento. Los autores concluyen que<\/p>\n\n\n\n

    \u201cLa espironolactona fue el f\u00e1rmaco m\u00e1s eficaz para el tratamiento de la hipertensi\u00f3n resistente a\u00f1adido al tratamiento est\u00e1ndar.\u00bb<\/p><\/blockquote>\n\n\n\n

    La hipertensi\u00f3n resistente debe ser considerada como rara y se tendr\u00eda que redifinir con el tratamiento:<\/p>\n\n\n\n

    • IECA o ARA II<\/li>
    • Calcioantagonista<\/li>
    • Diur\u00e9tico tiaz\u00eddico<\/li>
    • Espironolactona<\/li><\/ul>\n\n\n\n
      \n\n\n\n

      M\u00e1s informaci\u00f3n:<\/strong><\/span> publicaci\u00f3n\u00a0y estudio.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Cuando hablamos de  hipertensi\u00f3n resistente, nos referimos a la presi\u00f3n arterial NO controlada tratada con los medicamentos est\u00e1ndar. Este tratamiento se basa en tres grupos farmacol\u00f3gicos recomendados para disminuir la presi\u00f3n arterial en la m\u00e1xima dosis tolerada: Inhibidor de la enzima convertidora de angiotensina (IECA) o antagonista de los receptores de angiotensina II (ARAII). Calcioantagonista […]<\/p>\n","protected":false},"author":362,"featured_media":2428,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[20,90,32,35,45],"class_list":{"0":"post-2427","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-divulgacion-cientifica","8":"tag-atencion-farmaceutica","9":"tag-divulgacion-cientifica","10":"tag-estudios","11":"tag-farmacologia","12":"tag-investigacion"},"yoast_head":"\nEfectos positivos de la espironolactona frente a la hipertension resistente<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blog.uchceu.es\/farmacia\/efectos-positivos-de-la-espironolactona-frente-a-la-hipertension-resistente\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Efectos positivos de la espironolactona frente a la hipertension resistente\" \/>\n<meta property=\"og:description\" content=\"Cuando hablamos de  hipertensi\u00f3n resistente, nos referimos a la presi\u00f3n arterial NO controlada tratada con los medicamentos est\u00e1ndar. Este tratamiento se basa en tres grupos farmacol\u00f3gicos recomendados para disminuir la presi\u00f3n arterial en la m\u00e1xima dosis tolerada: Inhibidor de la enzima convertidora de angiotensina (IECA) o antagonista de los receptores de angiotensina II (ARAII). 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